Spindle pole bodies
نویسندگان
چکیده
How did you become interested in plants? I began my graduate work with Phil Leder with the hope of making transgenic mice as a means towards understanding development in a multicellular organism. It turned out to be far more difficult and timeconsuming than I had bargained for. So when it became apparent that making transgenic plants was relatively easy, I jumped at the opportunity. I also thought that basic discoveries could be more easily translated to practical applications in plant biology than in the area of human health.
منابع مشابه
Meiosis in Coprinus. IV. Morphology and behaviour of spindle pole bodies.
Meiotic synchrony in the genus Coprinus has permitted the sequential study of spindle pole body (SPB) behaviour through the meiotic process. The SPBs are monoglobular in the young basidia immediately after the last premeiotic mitosis. From 10 to 15 h before karyogamy until pachytene, spindle pole bodies are not found. They become conspicuous in diplotene and persist until the completion of meio...
متن کاملStable reanaphase spindle positioning requires Bud6p and an apparent interaction between the spindle pole bodies and the neck
Stable reanaphase spindle positioning requires Bud6p and an apparent interaction between the spindle pole bodies and the neck.
متن کاملCentrosome composition and microtubule anchoring mechanisms.
Centrosomes of animal cells and spindle pole bodies of fungi are the major microtubule nucleating centers. Recent studies indicate that their capacity to organize microtubule arrays rests on elaborate control of the anchoring and release of the nucleated microtubules. Although common molecular mechanisms are likely to be involved in both cases, the centrosome from animal cells shows considerabl...
متن کاملEvidence for cell cycle-specific, spindle pole body-mediated, nuclear positioning in the fission yeast Schizosaccharomyces pombe.
Specific changes in spatial order occur during cell cycle progression in fission yeast. Growth of the rod-shaped cells is highly regulated and undergoes a cell cycle and size-regulated switch from monopolar to bipolar tip extension. During both phases of growth, the interphase nucleus is maintained in a central location. Following the separation of the genome to the cell tips in mitosis, the tw...
متن کاملStable preanaphase spindle positioning requires Bud6p and an apparent interaction between the spindle pole bodies and the neck.
Faithful partitioning of genetic material during cell division requires accurate spatial and temporal positioning of nuclei within dividing cells. In Saccharomyces cerevisiae, nuclear positioning is regulated by an elegant interplay between components of the actin and microtubule cytoskeletons. Regulators of this process include Bud6p (also referred to as the actin-interacting protein Aip3p) an...
متن کاملTINA Interacts with the NIMA Kinase in Aspergillus nidulans and Negatively Regulates Astral Microtubules during Metaphase Arrest□V
The tinA gene of Aspergillus nidulans encodes a protein that interacts with the NIMA mitotic protein kinase in a cell cycle-specific manner. Highly similar proteins are encoded in Neurospora crassa and Aspergillus fumigatus. TINA and NIMA preferentially interact in interphase and larger forms of TINA are generated during mitosis. Localization studies indicate that TINA is specifically localized...
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ورودعنوان ژورنال:
- Current Biology
دوره 23 شماره
صفحات -
تاریخ انتشار 2013